Muthiah MANOHARAN,Jayaprakash K. NAIR,Pachamuthu KANDASAMY,Shigeo MATSUDA,Alexander V. KELIN,Muthusamy JAYARAMAN,Kallanthottathil G. RAJEEV
申请号:
US14901945
公开号:
US20160376585A1
申请日:
2014.07.11
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to ligand conjugates of oligonucleotides (e.g., iRNA agents) and methods for their preparation. The ligands are derived primarily from monosaccharides These conjugates are useful for the in vivo delivery of oligonucleotides.