METHODS AND TREATMENTS USING TOLL-LIKE RECEPTOR AGONISTS TO MITIGATE HEMATOPOIETIC MYELOID LOSS, INCREASE GASTROINTESTINAL RECOVERY AND REDUCE TUMOR GROWTH
Jenny P.-Y. Ting,Willie June Brickey,Hao Guo,Cathryn Julia Robbins
申请号：
US16761063
公开号：
US20200282006A1
申请日:
2018.11.19
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided herein are methods of mitigating and/or preventing side effects from chemotherapy and/or radiotherapy in a subject by administering a therapeutically effective amount of a toll-like receptor 2/6 (TLR 2/6) ligand, including fibroblast-stimulating lipopeptide 1 (FSL-1). Methods of treating and/or preventing gastrointestinal disorders are also disclosed. Additionally, methods of increasing granulocyte colony-stimulating factor (G-CSF) production in a subject undergoing a medical treatment, including administering FSL-1 compositions, are provided.
