A pest seal for a recreational vehicle (RV) to seal the gap that exists between a hose and/or cable passing through an access port located within the service compartment of a RV. The pest seal is comprised of two halves that are joined together along a single edge with mirrored cutouts that are lined with a compressible foam formed along the joining edge so that when the two halves are brought together the cutouts allow for the passage of a hose or cable through the pest seal. Embodiments further comprise a semicircular flange formed on the underside of each halve of a radius slightly smaller than the radius of the access port or a hinge attaching the two halves at one end of the edge where the halves are joined. The halves may be joined together by any number of means such as but not limited to magnets, hook and loop fabric, and mechanical latches.