A long-wear equine diagnostic boot for use on the lower leg of a horse has a plurality of alignment ribs for locating a bladder against the horses limb when the boot is secured to the horses leg. An electronic diagnostic device retained and secured in the boot inflates the bladder upon activation to urge the bladder for engagement against the horse. The bladder transmits a signal via a pulse transmission tube to the electronic device. The boot is constructed of latex-free, breathable, lightweight, washable material which allows for safe, long-wearing of the boot.
