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COMPOUND, COMPOUND OR SALT THEREOF, PHARMACEUTICAL COMPOSITION, GLYCORTICOID RECEIVER MODULATOR, METHOD FOR PREVENTION AND / OR TREATMENT OF METABOLIC DISEASES, INFLAMMATORY DISEASES, NURSES, ALPHERE CARE DISEASES WITH HOMEOSTASE OR GLAUCOMA, AND USE AT LEAST ONE COMPOUND OR SALT OF THE SAME
专利权人:
LTD.;SANTEN PHARMACEUTICAL CO.
发明人:
MAMORU MATSUDA,TOSHIYUKI MORI,MASATO NAGATSUKA,SACHIKO KOBAYASHI,MASATOMO KATO,MIWA TAKAI
申请号:
BRPI0811262
公开号:
BRPI0811262A2
申请日:
2008.05.29
申请国别(地区):
BR
年份:
2014
代理人:
摘要:
The compounds represented in general formula (1) or a salt thereof are useful for glucocorticoid receptor modulators. In the formula, R 1 represents a lower alkyl group, a lower cycloalkyl group, an aryl group and the like; R 2 represents a hydrogen atom, a lower alkyl group and the like; R 3 represents a hydrogen atom, a lower alkyl group and the like; R 4 and R 5 represent a hydrogen atom, a lower alkyl group and the like; R 6 represents a hydrogen atom, a lower alkyl group and the like; R 7 represents a hydrogen atom, a lower alkyl group, a lower alkenyl group and the like; W represents an oxygen atom, a sulfur atom, NR 8 and the like; R 8 represents a hydrogen atom, a lower alkyl group and the like; X represents an oxygen atom or a sulfur atom; Y represents a lower alkylene group and the like; Z represents an oxygen atom, a sulfur atom, NR 9 , OCO or OSO 2 ; R 9 represents a hydrogen atom, a lower alkyl group and the like respectively.
来源网站:
中国工程科技知识中心
来源网址:
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