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A continuous process for preparing microspheres and microspheres prepared thereby
专利权人:
发明人:
申请号:
EP14168217.9
公开号:
EP2803351A1
申请日:
2014.05.14
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The present invention relates to a continuous process for preparing microspheres and microspheres prepared thereby, and in particular, a process for preparing microspheres comprising steps of injecting a first emulsion and a second emulsion at the same time to form microspheres instantaneously, applying high pressure to the microspheres formed, and injecting the microspheres into an agitator, wherein the steps can be carried out continuously, and microspheres prepared thereby.When microspheres are prepared using the method of the present invention, scale variables, which have been the biggest disadvantage in existing preparation methods of microspheres, can be significantly reduced, drug encapsulation efficiency can be improved, and small and uniform particles can be obtained.
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