An information processing apparatus to register an ultrasonic image and a three-dimensional medical image at high speed is disclosed. The information processing apparatus includes: a medical image acquisition unit which acquires a medical image captured by a medical imaging apparatus in which an imaging unit captures an image of an object at a non-contact position with respect to the object, an ultrasonic image acquisition unit which acquires an ultrasonic image captured by an ultrasonic imaging apparatus in which an ultrasonic probe captures an image of the object at a position in contact with a surface of the object, and a coordinate transformation unit which transforms coordinates of the medical image or ultrasonic image with reference to the contact position on the ultrasonic image, so that image information of the medical image matches that of the ultrasonic image.
