Paul Algate,Stephanie Jane Clegg,Jennifer L. Craigen,Paul Andrew Hamblin,Alan Peter Lewis,Patrick Mayes,Radha Shah Parmar,Trevor Anthony Kenneth Wattam
申请号:
US14974675
公开号:
US20160193358A1
申请日:
2015.12.18
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.