Anti-plant antibodies or their allies, which contain CDRS sequences containing up to 17 amino acids, are associated with BAUCIZUBA or RANIBIZUBA antibodies, nucleic acids, carriers, Huesped cells, production methods, antibody-pharmacodynamic copolymers and synthetic compounds. And I used it to treat cancer.
HARDING FIONA,AKAMATSU YOSHIKO, DUBRIDGE ROBERT B, POWERS DAVID B,
申请号：
CL2011003182
公开号：
CL2011003182A1
申请日:
2011.12.15
申请国别(地区):
CL
年份:
2012
代理人:
摘要：
The anti VEGF antibody or its binding part includes CDRs containing carbamate sequence. Compared with the CDRs sequence of bevazumab or ranibizomb antibody, there are up to 17 mutations； nucleic acid； vector； host cell； production method； antibody drug binding； composition； and use for cancer treatment.Anticuerpo anti-VEGF o fragmento de unión del mismo que comprende CDRS con secuencias aminoacídicas con hasta 17 mutaciones respecto a las secuencias CDRS del anticuerpo bevacizumab o ranibizumab； ácido nucleico； vector； célula huésped； método de producción； conjugado anticuerpo-fármaco； composición； y uso para tratar cáncer.
