A population of renal proximal tubular cell (PTC)-like cells differentiated from a population of induced pluripotent stem cells (iPSCs) seeded at a density of about 5 000 to about 10 000 viable cells/cm 2 , in renal epithelial cell culture medium in the presence of one or more extracellular matrix molecule, bone morphogenic protein 2, and bone morphogenic protein 7, for a period of from about 7 to about 10 days. A bioengineered tissue graft comprising a matrix, seeded with the population of cells. A bioartificial kidney device containing the population of cells for use in the treatment of a renal related disorder in a subject. The population of cells or the bioengineered tissue graft for use in treatment of a renal related disorder in a subject.
