The Powerline Communication (“PLC”) systems and methods described allow for bi-directional communication along an AC or DC conductor between a first device and at least a second device comprising a medical device system. Generally, two devices within a sterile field may communicate with each other by PLC or a first device within a sterile field may communicate with a second device that is outside the sterile field by PLC. More specifically, a controller unit may communicate with a saline, or other fluid, pump to achieve a variety of functional purposes. Similarly, a measurement device may share measured data with another device.