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СПОСОБЫ И КОМПОЗИЦИИ ДЛЯ ЛЕЧЕНИЯ САХАРНОГО ДИАБЕТА И ДИСЛИПИДЕМИИ
专利权人:
КАРЕУС ТЕРАПЬЮТИКС; СА (CH)
发明人:
КХАННА Иш (US),ПИЛЛАРИСЕТТИ Сиварам (US)
申请号:
RU2013118021/15
公开号:
RU2013118021A
申请日:
2011.09.20
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A composition comprising at least one compound according to Formula I:, its stereoisomers and / or pharmaceutically acceptable salts gdeRvybran from the group consisting of hydroxy, alkoxy, amine, alkyl, haloalkyl, NHSOR or NHCOR, wherein R is selected from alkyl or cycloalkyl, NHR , wherein R is alkyl or cycloalkyl optionally substituted with hydroxy or alkoxy group nand nnezavisimo selected from 0, 1 and 2 at least one of R c and R / or R Robrazuyut cyclic ring containing 3-8 carbon atoms, optionally comprising alkyl groups, het roatomy or functional groups such as O, N, SO r and R or r and R, when they do not form a cyclic ring, then they optionally are independently selected from hydrogen, alkyl, branched alkyl and cycloalkyl Loboznachaet linear aliphatic chain optionally containing from 4 to 16 carbon atoms, optionally substituted one or more times by alkyl, branched alkyl, cycloalkyl or aryl are independently selected from hydrogen, alkoxy, hydroxy, alkyl, haloalkyl, cycloalkyl, heterocycloalkyl, heteroaryl, cyano or COR, wherein R c is selected from hydr hydroxy, alkyl, alkoxy, or amine, NHR , NHSOR or NHCOR Yoboznachaet oxygen or hydrogen Yyavlyaetsya optional, and when Yprisutstvuet, then Y and Yoboznachayut hydrogen, and when Yne present then Yoboznachaet carbonyl gruppu.2. Composition according to claim 1, wherein the compound has formula II:., stereoisomers and / or pharmaceutically acceptable salts thereof, wherein R are independently selected from the group consisting of hydroxy, alkoxy, alkyl, amine, NHR , wherein R is alkyl or cycloalkyl, optionally substituted with hydroxy or alkoxy group, NHSOR or NHCOR, wherein R is selected from alkyl or q1. Композиция, содержащая по меньшей мере одно соединение в соответствии с формулой I:,его стереоизомеры и/или фармацевтически приемлемые соли, гдеR1 выбран из группы, состоящей из гидрокси, алкокси, амина, алкила, галогеналкила, NHSO2R или NHCOR, где R выбран из алкила или циклоалкила, NHR, где R обозначает
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