To provide: a novel compound that inhibits Ax1 and is useful as a treatment for diseases caused by Ax1 hyperfunction, as a treatment for diseases related to Ax1 hyperfunction, and/or as a treatment for diseases involving Axl hyperfunction； a salt of said compound； or a crystal of said compound or salt. Provided are: a pyridone derivative having a tetrahydropyranyl methyl group represented by formula (I) and having various substituent groups； a salt of said derivative； or a crystal of said derivative or salt (Herein, R1, R2, R3, R4, R5, W, X, Y, and Z in formula (I) are synonymous with the definitions in the description.).本發明之課題係提供一種新穎化合物或其鹽、或彼等之結晶，其可用於抑制Axl，而治療由Axl之功能亢進所致的疾病、治療與Axl之功能亢進相關的疾病、及/或治療伴隨Axl之功能亢進的疾病。本發明之解決手段係提供具有各種取代基之以下述式(I)所示的具有四氫哌喃基甲基之吡啶酮衍生物或其鹽、或彼等之結晶(其中，式(I)中之R1、R2、R3、R4、R5、W、X、Y、Z各自如說明書中所定義同義。)式(I)
