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Oral vaccine having improved cellular immunity induction potency
专利权人:
发明人:
Takashi Nomura,Akiko Temma,Takahiro Nakazawa,Ryuichi Morishita,Il-Han Lee
申请号:
US14785364
公开号:
US09889186B2
申请日:
2014.04.18
申请国别(地区):
US
年份:
2018
代理人:
摘要:
An oral preparation for the prophylaxis or treatment of a disease with infection by a pathogen, containing a killed lactic acid bacterium expressing, on the surface, an antigen of the pathogen, or a microparticulated form thereof, which has an average particle size of 2.68-30 μm. An oral preparation for inducing cellular immunity to a target antigen, containing a killed lactic acid bacterium expressing the target antigen on the surface or a microparticulated form thereof, which has a particle size of 2.68-30 μm.
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