RHEIN BIOTECH GESELLSCHAFT FUER NEUE BIOTECHNOLOGISCHE PROZESSE UND
发明人:
MELBER, KARL
申请号:
HK07105918.1
公开号:
HK1100812B
申请日:
2007.06.05
申请国别(地区):
HK
年份:
2013
代理人:
摘要:
The present invention is a composition that comprises at least two hepatitis B virus surface antigens (HBsAgs), fragments thereof and/or nucleic acids encoding them, the HBsAgs differing in HBV genotype in the S region and/or pre-S 1 region and the composition containing no HBV core antigen (HBcAg) or nucleic acid encoding that antigen. The present invention also includes pharmaceutical compositions, especially vaccines, comprising these compositions for the prevention and/or treatment of an HBV infection or an HBV-mediated disease. The present invention further includes a method of preparing a patient-specific medicament for the therapeutic treatment of hepatitis B.