PROBLEM TO BE SOLVED: To provide a compound that has a strong Tyrosyl DNA Phosphodiesterase inhibitory activity, and can be used as pharmaceuticals.SOLUTION: The cyclic enone compound is exemplified by formula (4f) and formula (4e), and a therapeutic agent of cancer and a method of a treatment of a cancer use the same.COPYRIGHT: (C)2013,JPO&INPIT【課題】強いTyrosyl DNA Phosphodiesterase阻害活性を持ち、医薬品として利用可能な化合物の提供。【解決手段】下記に例示される環状エノン化合物、並びにそれを利用した癌の治療薬、及び癌の治療方法。【選択図】なし