A wire-guided curette and a method of thereof are described. The end portion ofthe curette is capable of scraping tissue for sampling. The end portion of thecurette can also excise and/or sweep away strictures that are impeding passagethrough the body lumen. The curette comprises a lumen for advancing the curetteover a wire guide and into body cavities that are normally difficult to access.The end portion of the curette that is performing the procedure comprises a scrapingelement that is affixed to a tubular shaft of the curette.
