OLIVARES MARTIN, MONICA,奥利瓦 墨妮卡,奧利瓦 墨妮卡,FONOLLA JOYA, JURISTO,佛诺拉 裘李斯,佛諾拉 裘李斯,DIAZ-ROPERO MEDINA, MARIA PAZ,戴兹 玛丽亚,戴茲 瑪麗亞,LOPEZ LARRAMENDI, JOSE LUIS,罗培兹 乔丝,羅培茲 喬絲,MENDOZA LADRON DE GUEVARA, NICOLAS,曼
申请号：
TW107140812
公开号：
TW201924692A
申请日:
2018.11.16
申请国别(地区):
TW
年份:
2019
代理人:
摘要：
The present invention relates to methods for increasing embryo implantation rate in an uterus, for preventing embryo implantation failure in a female subject suffering PCOS and for improving pregnancy rate comprising administering a composition comprising myo-inositol and D-chiro-Inositol in a weight ratio between 1:1 to 9:1 respectively to a female subject suffering PCOS. The invention also relates to a composition comprising myo-inositol and D-chiro-Inositol in a weight ratio between 1:1 to 9:1 respectively for use in the treatment or prevention of PCOS in a female subject, for use in the treatment or prevention of infertility in a female subject suffering polycystic ovary syndrome, or for use in preventing or reducing the risk of ovarian hyperstimulation syndrome in a female subject suffering polycystic ovary syndrome and subjected to ovary stimulation treatment. The invention also relates to a soft capsule comprising a) a soft capsule shell and b) a pharmaceutical composition comprising myo-inositol and D-chiro-Inositol in a weight ratio between 1:1 to 9:1 respectively.本發明涉及增加子宮中胚胎植入率，防止患有PCOS的女性受試者的胚胎植入失敗和提高妊娠率的方法，包括向患有PCOS的女性受試者施用包含肌肌醇和D-手性肌醇重量比分別為1：1至9：1的組合物。本發明還涉及包含肌肌醇和D-手性肌醇重量比分別為1：1至9：1的組合物，用於治療或預防女性受試者的PCOS，用於治療或預防患有多囊卵巢綜合症的女性受試者的不孕症，或用於預防或降低患有多囊卵巢綜合症並接受卵巢刺激治療的女性受試者中卵巢過度刺激綜合症的風險。本發明還涉及軟膠囊，其包含a）軟膠囊殼和b）包含肌肌醇和D-手性肌醇重量比分別為1：1至9：1的藥物組合物。
