This invention features that the enclosure body is grain configuration, it regards the enclosure body which includes the polypeptide and is isolated. In addition as for this invention, it regards the bacterial cell which includes the aforementioned enclosure body. This invention furthermore regards the aforementioned enclosure body and the constituent which includes the eukaryotic cell. In addition as for this invention, the aforementioned enclosure body and it regards the constituent which includes animal or plant system. In addition as for this invention, it regards use, as a medicine and a stimulus material of cell breeding of the aforementioned enclosure body and system regeneration.本発明は、封入体が粒子形態であることを特徴とする、ポリペプチドを含む単離された封入体に関する。本発明はまた、前記封入体を含む細菌細胞に関する。本発明はさらに、前記封入体および真核細胞を含む組成物に関する。本発明はまた、前記封入体および動物または植物組織を含む組成物に関する。本発明はまた、前記封入体の、細胞増殖および組織再生の医薬および刺激物質としての使用に関する。