A combination of scyllo-inositol and myo-inositol, wherein, the scyllo-inositol and myo-inositol are nutritional ingredients for use in the prevention or treatment of a condition selected from the group consisting of prediabetes, type II diabetes, gestational diabetes mellitus and a condition associated with any of the forgoing in a subject, and a composition comprising scyllo-inositol and myo-inositol.一種鯊肌醇(scyllo-inositol)與肌肌醇(myo-inositol)之組合,其中該鯊肌醇與該肌肌醇係用於預防或治療選自由下列所組成之群組的病況之營養成分:對象之糖尿病前期、第II型糖尿病、妊娠糖尿病、及與前述任一者相關聯之病況;及一種包含鯊肌醇與肌肌醇之組成物。