The invention provides compounds of first-order equation or salts acceptable on medicines in first-order equation.And their works and methods of useInhibiting the activity of Janukunsa (JAK) and contributing to the treatment of diseases related to Jacques'activity,Include,For instanceInflammation.Self-immunity disorderCancer.And other diseases: Current inventions offer compounds in formula one: or salt acceptable to medicines.As well as their compositions and methods of use,That inhibit the activity of January Kinase (Jak) and are useful in the treatment of diseases related to the activity of JAK including,For example,Aerated antidoteAutimmune disorders,Cancer.And other diseases.La presente invención proporciona compuestos de la Fórmula I: o sales farmacéuticamente aceptables de este, así como sus composiciones y métodos de uso, que inhiben la actividad de la Janus quinasa (JAK) y son útiles en el tratamiento de enfermedades relacionadas con la actividad de JAK, que incluyen, por ejemplo, trastornos inflamatorios, trastornos autoinmunitarios, cáncer, y otras enfermedades.The present invention provides compounds of Formula I: or pharmaceutically acceptable salts thereof, as well as their compositions and methods of use, that inhibit the activity of Janus kinase (JAK) and are useful in the treatment of diseases related to the activity of JAK including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.
