Freda D. MILLER,David KAPLAN,Kristen SMITH,Maryline PARIS,Sibel NASKA
申请号:
US14270021
公开号:
US20140234271A1
申请日:
2014.05.05
申请国别(地区):
US
年份:
2014
代理人:
摘要:
We have discovered that p63 inhibition results in increased cellular proliferation. We have also performed a screen for agents capable of increasing cellular proliferation, (e.g., of stem cells such as skin-derived precursors (SKPs)). The invention therefore invention provides compositions, methods, and kits for increasing proliferation of cells, using compounds that decrease p63 expression or activity or using the compounds described herein. The invention also features methods of using these compounds for increasing hair growth, improving skin health, or promoting skin repair in a subject.