CHERUVALLATH, ZACHARIA,GWALTNEY, STEPHEN L,JENNINGS, ANDREW JOHN,SABAT, MARK,STAFFORD, JEFFREY A,TANG, MINGNAM,WANG, HAIXIA
申请号：
NZ58908409
公开号：
NZ589084A
申请日:
2009.05.15
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
Disclosed are pyrazole-amide compounds represented by general formula (I). Examples of the compounds of formula (I) include: 2-(3-(cyclopropylsulfonyl)-1H-pyrazol-1-yl)-N-(5-methoxythiazolo[5,4-b ]pyridin-2-yl)-3-(tetrahydro-2H-pyran-4-yl)propanamide (S)-2-(3-(cyclopropylsulfonyl)-1H-pyrazol-1-yl)-N-(5-methoxythiazolo[5,4-b ]pyridin-2-yl)-3-(tetrahydro-2H-pyran-4-yl)propanamide and (R)-2-(3 -(cyclopropylsulfonyl)-1H-pyrazol-1-yl)-N-( 5-methoxythiazolo[5,4-b]pyridin-2-yl)-3-( tetrahydro-2H-pyran-4-yl)propanamide. The compounds are used to treat hyperglycemia, diabetes, dyslipidaemia, obesity, insulin resistance, metabolic syndrome, impaired glucose tolerance, polycystic ovary syndrome and cardiovascular disease.
