A method of manufacturing an absorbent article that can increase the bonding strength of the bonded portion between the absorbent structure and the waist panel without excessively increasing the amount of adhesive to be applied, is provided. A method of manufacturing an absorbent article (10) is a method of manufacturing an absorbent article including a waistline region (14, 15), a crotch region (16), and an absorber (11) disposed at least in the crotch region. The method of manufacturing comprises: a shaping step (S1) of forming a convexo-concave portion (57a) on a first sheet (51) composed of a nonwoven fabric disposed in the crotch region； an absorber disposing step (S6) of disposing the absorber on the first sheet； and an adhesion step (S8) of bonding the first sheet to a waistline sheet (18, 19) disposed in the waistline region with a first adhesive (28, 29) after the shaping step. The adhesion step includes applying at least part of the first adhesive to a region which overlaps with the convexo-concave portion and does not overlap with the absorber in at least one of the first sheet and the waistline sheet.
