N- (5S, 6S, 9R) - 5 -AMINO- 6 - (2, 3 - DIFLUOROPHENYL) -6, 7, 8, 9 - TETRAHYDRO - 5H - CYCLOHEPTA (B)PYRIDIN-9 -YL- 4 - (2 - OXO-2, 3 - DIHYDRO - 1H- IMIDAZO (4, 5 -B)PYRIDIN - 1 - YL) PIPERIDINE - 1 - CARBOXYLATE, HEMISULFATE SALT

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专利权人:

Bristol-Myers Squibb Company

发明人:

ROBERTS Daniel Richard,ROBERTS Daniel Richard,SCHARTMAN Richard Raymond,SCHARTMAN Richard Raymond,WEI Chenkou,WEI Chenkou

申请号：

SI201330759

公开号：

SI2820016T1

申请日:

2013.02.25

申请国别(地区):

SI

年份:

2017

代理人:

摘要：

Disclosed is a hemisulfate salt of Compound (I): and crystalline forms of the hemisulfate salt. Also disclosed are methods of using the hemisulfate salt of Compound (1) as a CGRP receptor antagonist, and pharmaceutical compositions comprising the hemisulfate salt of Compound (I). The hemisulfate salt of Compound (I) is useful in treating, preventing, or ameliorating disorders including migraine and other headaches, neurogenic vasodilation, neurogenic inflammation, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases such as asthma, and chronic obstructive pulmonary disease (COPD).

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