A composition of matter and method for treating compromised skin is disclosed, providing improved skin barrier repair and maintenance properties. The composition of matter comprises at least one lipid selected from a group consisting of lipids defined by a predetermined lipid profile and at least one skin nutrient selected from a group consisting of nutrients defined by a predetermined nutrient profile, but is substantially free of petrolatum. This composition of matter produced a surprising improvement when applied to cracked skin of, e.g., diabetes mellitus patients or other individuals with dry or damaged skin.
