FIELD: medicine.SUBSTANCE: invention relates to medicine, specifically to efferent therapy, and can be used during plasmapheresis. For this purpose, a device for plasmapheresis is proposed, which comprises a first conduit through which blood drawn from a mammalian patient travels under the influence of a pump, a separator for separating cellular components of said blood from plasma, a column device through which said plasma flows. Column device selectively removes galectin-3 (gal-3) and other substances associated with galectin-3, including TNF receptor blockers from said plasma to provide treated plasma. Device also comprises a second conduit, which receives said treated plasma after passing through said column device and in which said plasma to be treated is combined with blood cells separated in said separator before returning to said patient. Said first and second conduits provide for a substantially continuous flow of said blood and plasma from said patient and return to said mammal. Device also comprises at least one additional column device for removing a plasma component other than gal-3.EFFECT: disclosed device provides not only the removal of galectin-3 or other galectins from blood, but also the removal of other, including potentially dangerous, factors and also provides for the introduction into the blood of additional therapeutic factors when returning the blood to the mammalian patient.14 cl, 3 dwgИзобретение относится к медицине, а именно к эфферентной терапии, и может быть использовано при проведении плазмафереза. Для этого предложено устройство для проведения плазмафереза, которое содержит первую трубку, по которой кровь, выводимая из пациента млекопитающего, передвигается под действием насоса, сепаратор для отделения клеточных компонентов указанной крови от плазмы, колонковое устройство, через которое протекает указанная плазма. При этом колонковое устройство избирательно удаляет галектин-3 (gal-3) и другие вещества, ассоциированные с галектином-3,
