Norrin Mutant Polypeptides, Methods of Making and Uses Thereof

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专利权人:

VAN ANDEL RESEARCH INSTITUTE

发明人:

Huaqiang Eric Xu,Jiyuan Ke

申请号：

US14769166

公开号：

US20150376252A1

申请日:

2014.02.20

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention relates to Norrin mutant polypeptides that inhibit or reduce angiogenesis in various tissues. Methods for synthesizing recombinant Norrin and Norrin mutant polypeptides are provided. Methods of inhibiting or reducing aberrant angiogenesis comprise contacting a tissue undergoing aberrant angiogenesis with a composition comprising an isolated Norrin C mutant polypeptide.

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中国工程科技知识中心

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http://www.ckcest.cn/home/