Biocompatible and implantable in the human body plastic material, for the obtainment of a device that can be implanted in the human body or a spacer device in order to treat a bone or a joint location, comprising an acrylic resin or polyethylene (PE) or low density polyethylene or high density polyethylene or ultra-high molecular weight polyethylene (UHMWPE) or polypropylene or polyamide or polyetheretherketone (PEEK) or a thermosetting resin or a mixture of the same, wherein the material can be molded and comprises at least one pharmaceutical or medical substance; device implantable in the human body or spacer device for treating a bone or a joint location, obtained by the material above and method for manufacturing the material according to the present invention.