Pravin L. Kotian,Yarlagadda S. Badu,V. Satish Kumar,Weihe Zhang,Lakshminarayana Vogeti
申请号:
US15764071
公开号:
US20180362458A1
申请日:
2016.09.30
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed are compounds of formula I, and pharmaceutically acceptable salts thereof. The compounds are inhibitors of plasma kallikrein. Also provided are pharmaceutical compositions comprising at least one compound of the invention, and methods involving use of the compounds and compositions of the invention in the treatment and prevention of diseases and conditions characterized by unwanted plasma kallikrein activity.