A system and method for treating vessel in skin is disclosed. The system may include two or more electrodes that may be inserted in skin to deliver electrical signal to target vessel therein, an electrical signal generator electrically coupled to the plurality of electrodes, and a power supply unit for supplying power to the electrical signal generator. The system and method may be employed to selectively reduce hypervascularity in the dermis or epidermis by generating thermal damage thereto or inducing phagocytosis or apoptosis of vascular cell in order to treat melasma, dermal melasma, hyperpigmentation, hypopigmentation, rosacea, flushing, erythema, or telangiectasia, while lowering the risk of excessive heating of the skin vessel encountered in and reducing the rate of re-occurrence of rebounded vascularization associated with conventional LASER treatments for melasma, dermal melasma, hyperpigmentation, hypopigmentation, rosacea, flushing, erythema, or telangiectasia.
