The present invention relates to a method for promoting virus infection and enhancing production using a cell line in which the function of the Bst2 gene has been lost, and more specifically, removing the Bst2 gene from a cell line capable of producing virus and promoting virus release and hosting. The present invention relates to a method for increasing production by promoting infection with a target virus in addition to the cell death suppression effect. According to the present invention, the method for promoting infection and enhancing production of a target virus using a cell line that has lost the function of the Bst2 gene can improve the production yield of the target virus and the antigen protein. Useful for vaccine production for prevention.
