The present invention involves a cleaning sleeve for cleaning the oral cavity, suitable to be applied over a finger or a tool to clean the inside of the oral cavity. The cleaning sleeve has a flat-layered structure comprising a sleeve portion formed by laminated sheet-like fabrics and a grip portion formed by a single-layer sheet-like fabric, wherein the sleeve portion comprises a working layer and a sleeve layer; the working layer and the sleeve layer form a head at the top, of the cleaning sleeve; and the grip portion is integrally extended from the Working layer. The cleaning sleeve is formed by ultrasonically bonding the two sides of a piece of folded degradable nonwoven fabric.