Zenghe Liu,Brian Otis,Jaclyn Leverett Wasson,William James Biederman
申请号：
US15043817
公开号：
US20160235346A1
申请日:
2016.02.15
申请国别(地区):
US
年份:
2016
代理人:
摘要：
An electrochemical sensor of a flexible, body-mountable analyte sensing device is provided. The electrochemical sensor is disposed on a flexible sensor probe that is configured to penetrate the skin such that the electrochemical sensor disposed on the sensor probe can detect an analyte in interstitial fluid. The electrochemical sensor is made sensitive to the analyte by disposing a substance that selectively binds to reacts with, catalyzes a reaction of, or otherwise selectively interacts with the analyte. The substance is localized by crosslinking on the surface of an electrode and/or by being disposed in a polymer layer disposed on the electrode. The polymer layer can be a hydrogel. Further, a hydrogel layer can be formed on the sensor probe to protect elements of the sensor probe and to increase the biocompatibility of the sensor probe.
