NEISSERIA-MENINGITIDIS-FHBP VARIANT AND ITS APPLICATION FOR VACCINATION

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专利权人:

Oxford University Innovation Limited

发明人:

TANG, Christoph,LEA, Susan

申请号：

DK13765388

公开号：

DK2887956T3

申请日:

2013.08.22

申请国别(地区):

DK

年份:

2019

代理人:

摘要：

The invention relates to a modified V2 fHbp having increased stability over a wild type V2 fHbp； a modified V2 fHbp having an amino acid sequence with at least 85% identity to the sequence of Seq ID No: 1, wherein both Ser137 and Gly138 are mutated or both Val112 and Leu114 are mutated； immunogenic, pharmaceutical and vaccine compositions； nucleic acid and a host cell； and methods of use of such compositions.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/