University of Medicine and Dentistry of New Jersey
发明人:
Ma, Jianjie,Weisleder, Noah
申请号：
AU2009270826
公开号：
AU2009270826B2
申请日:
2009.07.16
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
Disclosed herein are compositions and methods for treatment of muscle dysfunction (including sarcopenia) and other diseases involving skeletal musle, including age-related muscle dysfunction. In addition, the invention relates to therapeutic compositions comprising nucleotides and/or polypeptides of the invention in combination with a pharmaceutically acceptable carrier, wherein the composition facilitates the treatment of skeletal musle disorder, including those related to thr normal aging process. Moreover, the invention relates to the treatment and/or prevention of pathological conditions associated with altered intracellular Ca2+ reulgation and disrupted membrane structure that occurs when the expression levels of MG29 are reduced.
