Guy Cavet;Carol O'Brien;Mark Lackner;Ajay Pandita;Lukas C. Amler
发明人:
Mark Lackner,Lukas C. Amler,Guy Cavet,Carol O'Brien,Ajay Pandita,Carol OBrien
申请号:
US12922420
公开号:
US09879267B2
申请日:
2009.03.12
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Methods and compositions are provided to determine if a cancer is resistant to treatment with anti-mitotic agents, including treatment with T-DM1. The methods relate to determining if the ABCC3 gene is amplified and/or overexpressed in the cancer.