Provided are methods for the treatment and prevention of fibrosis at a medical implant site in a subject, by administering a microporous gel to the medical implant site. Also provided are methods of preventing or treating an infection at the medical implant site in a subject. Also disclosed herein are methods for promoting healing of a wound or surgical incision at a medical implant site in a subject, by administering a microporous gel to the medical implant site. The microporous gel may be fluidic during application and annealed or crosslinked after application. The microporous gels may contain various therapeutic agents, including antibiotics and analgesics, throughout the gel.