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Thienopyridyl compounds that inhibit vanilloid receptor subtype 1 (VR1) and uses thereof
专利权人:
Chih-hung Lee;Arthur R. Gomtsyan;Sean T Turner;Tammie K Jinkerson
发明人:
Sean T Turner,Tammie K Jinkerson,Arthur R. Gomtsyan,Chih-hung Lee
申请号:
US12968666
公开号:
US08501769B2
申请日:
2010.12.15
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention discloses fused thienopyridyl compounds of general formula (I)wherein X1-X6, R5-R7, Z1 and L are as defined in the description. The resent invention also discloses a method for inhibiting the VR1 receptor in mammals using these compounds, a method for controlling pain, urinary incontinence, bladder overactivity, and inflammatory thermal hyperalgesia in mammals, and pharmaceutical compositions including those compounds.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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