Disclosed herein is the use of an extract from an Aster species for the preparation of a medicament for the treatment of pain. The extract is extracted from fresh and/or dried roots and rhizomes of a Tatarian aster (Aster tartaricus) plant, in which the extraction is performed by use of water or 10-95% (v/v) ethanol as an extractant to obtain an extraction mixture. In some embodiments, the extraction mixture is further subject to column chromatography, in which the cloumn was eluted in sequence with water, and at least one eluent other than water.