In particular, the present disclosure provides compositions and pharmaceutical compositions thereof that bind to soluble biomolecules and inhibit their biological activity. The composition comprises a plurality of particles that specifically bind to a target, e.g., a soluble biomolecule or a biomolecule on the surface of a pathogen, and inhibit the target (or pathogen) from interacting with other molecules or cells. May be included. [Selection] Figure 7本開示は、特に、可溶性生体分子と結合し、その生物学的活性を阻害する組成物及びその医薬組成物を提供する。本組成物は、標的、例えば、可溶性生体分子又は病原体の表面にある生体分子に特異的に結合し、標的(又は病原体)が他の分子又は細胞と相互作用することを阻害する複数の粒子を含んでもよい。【選択図】図7