Johannes L. Zakrzewski,Marcel R. M. Van Den Brink,Michel Sadelain
申请号：
US12865592
公开号：
US10059923B2
申请日:
2009.01.30
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The inventive subject matter relates to methods for treating a T-cell deficiency in a subject in need thereof, comprising administering to said subject a T-cell precursor isolated from an allogeneic donor, provided that said allogeneic donor is not MHC-matched to said subject. The inventive methods can be further enhanced by genetic engineering for targeted immunotherapy.
