FORMULATION POUR UN ANTICORPS ANTI-.ALPHA.4.BETA.7

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专利权人:

INC.;MILLENNIUM PHARMACEUTICALS

发明人:

DILUZIO, WILLOW,NGUYEN, PHUONG M.,VARGA, CSANAD M.,PALANIAPPAN, VAITHIANATHAN,BROWN, JASON,FOX, IRVING H.,SCHOLZ, CATHERINE,ROSARIO, MARIA,JENKINS, HELEN

申请号：

CA3051418

公开号：

CA3051418A1

申请日:

2012.05.02

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

Antibody formulations are described comprising a mixture of an anti-.alpha.4.beta.7 antibody, anantioxidant or chelator, and at least one free amino acid. The disclosedformulations mayhave improved stability, reduced aggregate formation, or both. The presentinvention furtherprovides a safe dosing regimen of these antibody formulations that is easy tofollow, andwhich results in a therapeutically effective amount of the anti-.alpha.4.beta.7 antibody in vivo.

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