TRANSGENIC MAMMALLS MODIFIED IN BRI PROTEIN EXPRESSION

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专利权人:

Luciano DAdamio

发明人:

Luciano DAdamio,Luca Giliberto

申请号：

US13477397

公开号：

US20130133090A1

申请日:

2012.05.22

申请国别(地区):

US

年份:

2013

代理人:

摘要：

Provided are non-human mammals comprising a knock-in nucleic acid sequence capable of causing an alteration of expression of wild-type Bri2 in the mammal or a knockout of wild-type Bri2. Also provided are the non-human mammals as a model for Alzheimers disease.

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中国工程科技知识中心

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http://www.ckcest.cn/home/