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A METHOD OF PRODUCING A DELIVERY DEVICE
专利权人:
发明人:
申请号:
EP12851092.2
公开号:
EP2782556A1
申请日:
2012.11.23
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
A method of producing a delivery device for delivering a chemical compound includes i) providing an interpenetrating polymer substrate (IP substrate) having a first continuous polymer comprising rubber and a second polymer having hydrogel or a hydrogelable precursor, where the second polymer is interpenetrating in the first polymer ii) providing the chemical compound and a loading solvent for the chemical compound and iii) loading the IP substrate with the chemical compound by subjecting the IP substrate to the loading solvent having the chemical compound under conditions where the loading solvent at least partially swells the second polymer. The chemical compound, the second polymer and the loading solvent are selected such that the work of adhesion (Whc) between the second polymer and the chemical compound during at least a part of the loading is at least about 0 J/m2.
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