PROBLEM TO BE SOLVED: To provide an inhalation type pharmaceutical composition for the treatment of diabetes containing a first gas and atomization agent, and to provide a preparation method thereof.SOLUTION: In an inhalation type pharmaceutical composition for the treatment of diabetes, a first gas contains hydrogen, the gas volume concentration of hydrogen in the inhalation type pharmaceutical composition is between 2 and 96%, and an atomization agent is metformin hydrochloride, glibenclamide, Glucobay, rosiglitazone maleate, insulin, or any combination thereof. The inhalation type pharmaceutical composition further contains oxygen in the first gas in the volume ratio obtained by electrolysis of water of 2:1. Or the inhalation type pharmaceutical composition contains, as a second gas, gas selected from vapor, inert gas, air, oxygen, or any combination thereof in order to reduce hydrogen.【課題】第１のガスと霧化薬剤とを含む糖尿病の治療用の吸入型医薬組成物、およびその調製方法の提供。【解決手段】第１のガスは水素を含み、吸入型医薬組成物中の水素のガス体積濃度は、２～９６％の間であり、霧化薬剤は、メトホルミン塩酸塩、グリベンクラミド、グルコバイ、マレイン酸ロシグリタゾン、インスリン、又はそれらの任意の組合せである糖尿病の治療用の吸入型医薬組成物。第１ガスに酸素を更に含み、水の電気分解で得られる体積比で２：１である吸入型医薬組成物。又は、水素を低減する目的で水蒸気、不活性ガス、空気又は酸素を任意の組み合せから選択されるガスを第２ガスとして含む吸入型医薬組成物。【選択図】図１
