The present invention relates a botulinum toxin prefilled syringe systemwith desirable injection force characteristics, in particular low glidingforce and lowbreak loose force, comprising a syringe barrel of glass containing a liquidbotulinumtoxin composition, a plunger stopper and a closure device such as a tip cap ora needleshield. In addition, the present invention relates to a kit comprising thebotulinum toxinprefilled syringe system, and optionally instructions for use, and to the useof the botulinumtoxin prefilled syringe system in therapeutic and cosmetic applications
