PROCESS FOR PREPARING PLEUROMUTILINS

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专利权人:

NABRIVA THERAPEUTICS AG

发明人:

INGOLF MACHER,ANDREAS BERGER,MARTIN DECRISTOFORO

申请号：

BRPI0719205

公开号：

BRPI0719205A2

申请日:

2007.10.03

申请国别(地区):

BR

年份:

2014

代理人:

摘要：

A process for the preparation of 14-O-[(N-(3-methyl-2-amino-butyryl-piperidinyl)sulfanyl) acetyl]mutilins of formula feasible for large-scale production of high purity products, and wherein the carbon atom at the piperidine ring attached to the sulphur atom is either in the (S)-configuration or in the (R)-configuration, and a new crystalline form of 14-O-[(N-3-methyl-2-(R)-amino-butyryl-piperidine-3(S)-yl)sulfanyl)acetyl]mutilin - hydrochloride.

来源网站：

中国工程科技知识中心

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