NEW ANTI-HUMAN PAI-1 ANTIBODY

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专利权人:

Astellas Pharma Inc.

发明人:

TANAKA, Hirotsugu,YOSHINO, Masayasu

申请号：

EP15751458

公开号：

EP3109320A4

申请日:

2015.02.20

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

[Problem] To provide an anti-human PAI-1 antibody for preventing or treating pulmonary fibrosis by binding to active human PAI-1 and inhibiting effects mediated by the active human PAI-1. [Means for Solution] The present inventors have investigated anti-PAI-1 antibodies and consequently have provided an anti-human PAI-1 antibody comprising a heavy chain variable region consisting of the amino acid sequence of amino acid numbers 1 to 118 of SEQ ID NO: 2 and a light chain variable region consisting of the amino acid sequence of amino acid numbers 1 to 108 of SEQ ID NO: 4.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/