A process for the preparation of a topography for improved protein adherence on a body made of titanium or a titanium alloy wherein the process includes the subsequent steps of pre-treating the surface including etching the surface with an etching solution containing a mineral acid, and forming on the pre-treated surface obtained under titanate-including sub-microscopic structures by treating the pre-treated surface with an aqueous solution containing an oxidative agent, the sub-microscopic structures extending in at least two dimensions to 1 μm at most.